ISOLATION AND CHARACTERIZATION OF FULL-LENGTH GENES ENCODING THE ANTI-HUMAN CD45 ANTIBODY FROM THE HYBRIDOMA CELL LINE 16E8-F2

Isolation and characterization of full-length genes encoding the anti-human CD45 antibody from the hybridoma cell line 16E8-F2

Though the hybridoma technology has been widely applied in the production of monoclonal antibodies, it has existed some disadvantages including low yield and genetic instability.Therefore, an alternative approach should be taken into account.Recently, recombinant monoclonal antibody technology has emerged as the best choice to cure hybridoma relate

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Cell competition, cooperation, and cancer

Complex multicellular organisms Scatter Tray require quantitative and qualitative assessments on each of their constitutive cell types to ensure coordinated and cooperative behavior towards overall functional proficiency.Cell competition represents one of the operating arms of such quality control mechanisms and relies on fitness comparison among i

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